Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.44 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425127 | 0.88 | PDE5A (0.41) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29140531 | 0.83 | PDE5A (0.43) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28087191 | 0.81 | STAT3 (0.42) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28169160 | 0.81 | STAT3 (0.42) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7867501 | 0.80 | STAT3 (0.40) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7860935 | 0.80 | STAT3 (0.40) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28839759 | 0.77 | TSHR (0.55) | TSHR | |
| SCHEMBL28246174 | 0.77 | HPGD (0.42) | LMNAMAPT | |
| SCHEMBL30733335 | 0.76 | STAT3 (0.47) | PDE5APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29901368 | 0.75 | PDE5A (0.48) | PDE5APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6263762-A | — | — | None | — | — | JP | disclosed |
| JP-H06263762-A | PHYNYLPORPHYRIN COMPOUND | YAMAMOTO IWAO | 1994-09-20 | — | — | JP | disclosed |