Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860935 | 1.00 | STAT3 (0.40) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL9425127 | 0.88 | PDE5A (0.41) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL30733335 | 0.81 | STAT3 (0.47) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15282931 | 0.81 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL9425136 | 0.80 | PDE5A (0.44) | PDE5APDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL27856204 | 0.79 | STAT3 (0.50) | STAT3STAT1 | |
| SCHEMBL14848838 | 0.78 | STAT3 (0.44) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL21523873 | 0.77 | STAT3 (0.53) | STAT3STAT1 | |
| SCHEMBL29395084 | 0.77 | STAT3 (0.50) | STAT3STAT1PDE5APDE4APDE4B | |
| SCHEMBL15298526 | 0.77 | STAT3 (0.41) | STAT3STAT1PDE5APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107971-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | Destiny Pharma Limited (GB) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012512-A1 | PORPHYRIN DERIVATIVES, THEIR USE IN PHOTODYNAMIC THERAPY AND MEDICAL DEVICES CONTAINING THEM | DESTINY PHARMA LIMITED (GB) | 2000-03-09 | — | — | WO | disclosed |