Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815830 | 0.91 | ABCB1 (0.57) | POLBABCB1CYP3A4CYP2C9HTT | |
| SCHEMBL9425505 | 0.85 | HTT (0.64) | POLBABCB1CYP3A4CYP2C9HTT | |
| SCHEMBL9714597 | 0.82 | ABCB1 (0.76) | POLBABCB1CYP3A4CYP2C9MEN1 | |
| SCHEMBL9714306 | 0.81 | POLB (0.68) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL9815833 | 0.81 | ABCB1 (0.66) | POLBABCB1CYP3A4CYP2C9HTT | |
| SCHEMBL9714603 | 0.80 | CYP3A4 (0.73) | POLBABCB1CYP3A4CYP2C9 | |
| SCHEMBL8166763 | 0.80 | POLB (0.74) | POLBABCB1CYP3A4CYP2C9MEN1 | |
| SCHEMBL9652010 | 0.80 | POLB (0.74) | POLBABCB1CYP3A4CYP2C9MEN1 | |
| SCHEMBL8166298 | 0.80 | POLB (0.68) | POLBCYP3A4CYP2C9HTTMEN1 | |
| SCHEMBL9714310 | 0.79 | POLB (0.68) | POLBABCB1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |