Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815886 | 0.91 | CTNNB1 (0.52) | CTNNB1WNT3AABCB1GRM4 | |
| SCHEMBL8172818 | 0.83 | ABCB1 (0.47) | ABCB1 | |
| SCHEMBL9815861 | 0.83 | ABCB1 (0.47) | ABCB1 | |
| SCHEMBL9714393 | 0.81 | POLB (0.67) | ABCB1 | |
| SCHEMBL9815834 | 0.80 | ABCB1 (0.54) | ABCB1 | |
| SCHEMBL8166298 | 0.80 | POLB (0.68) | — | |
| SCHEMBL8173265 | 0.79 | ABCB1 (0.50) | ABCB1 | |
| SCHEMBL9425269 | 0.78 | GRM4 (0.53) | ABCB1GRM4 | |
| SCHEMBL8173935 | 0.78 | POLB (0.55) | — | |
| SCHEMBL9425386 | 0.78 | ABCB1 (0.62) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354762-A | Insecticides | ROHM AND HAAS COMPANY (US) | 1994-10-11 | — | — | US | disclosed |
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0253468-A2 | Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |