SCHEMBL9425831

SCHEMBL9425831

CC(C)(C)N(NC(=O)c1cccnc1Br)C(=O)c1ccc(Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.50
POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815764 0.91 ABCB1 (0.51) ABCB1
SCHEMBL9425422 0.83 POLB (0.55) ABCB1POLB
SCHEMBL9714486 0.80 ABCB1 (0.70) ABCB1
SCHEMBL10719200 0.80 ABCB1 (0.52) ABCB1
SCHEMBL9426253 0.80 POLB (0.62) ABCB1POLB
SCHEMBL9714466 0.79 ABCB1 (0.70) ABCB1POLB
SCHEMBL10720334 0.78 ABCB1 (0.57) ABCB1POLB
SCHEMBL9714227 0.78 POLB (0.71) POLB
SCHEMBL9815847 0.78 POLB (0.55) POLB
SCHEMBL10721292 0.76 LMNA (0.61) ABCB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5354762-A Insecticides ROHM AND HAAS COMPANY (US) 1994-10-11 US disclosed
EP-0253468-B1 SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES ROHM AND HAAS COMPANY (US) 1991-11-06 EP disclosed
EP-0253468-A2 Six-membered heterocyclic derivatives of N'substituted-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1988-01-20 EP disclosed