Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | SELP | P16109 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | CASP2 | P42575 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12245384 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL19417124 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL12942436 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL399954 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL14065637 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL12836915 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL17817134 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL3495212 | 1.00 | NAAA (0.59) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL23193936 | 0.98 | NAAA (0.57) | NAAAFAAHDNM1SELPCNR1 | |
| SCHEMBL10579388 | 0.98 | NAAA (0.57) | NAAAFAAHDNM1SELPCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358946-A | Heterocycle-substituted amides, carbamates and ureas as agents for the treatment of atherosclerosis | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-10-25 | — | — | US | disclosed |
| US-4814382-A | HYDROXYALKYL CARBAMATE REACTIVE DILUENTS, FILMS | UNION CARBIDE CORPORATION (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0285650-A1 | SOLVENT BORNE HIGH SOLIDS COATING COMPOSITIONS. | UNION CARBIDE CORP (US) | 1988-10-12 | — | — | EP | disclosed |
| WO-1988002766-A1 | SOLVENT BORNE HIGH SOLIDS COATING COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1988-04-21 | — | — | WO | disclosed |