Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922571 | 0.84 | USP30 (0.30) | — | |
| SCHEMBL9426059 | 0.82 | CHRNB2 (0.37) | CHRNB2CHRNA3CHRNA4CHRNB4CYP1A2 | |
| SCHEMBL1290235 | 0.79 | MAPT (0.46) | EPHX1ALDH1A1 | |
| SCHEMBL9381187 | 0.76 | BPTF (0.33) | BPTFNOTUMCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL9425981 | 0.75 | HPGD (0.45) | CHRNB2CHRNA3CHRNA4CHRNB4EPHX1 | |
| SCHEMBL34474060 | 0.74 | POLB (0.45) | CYP1A2ALDH1A1MAPK1DPP4 | |
| SCHEMBL12801362 | 0.74 | NOTUM (0.38) | NOTUMCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL2378450 | 0.74 | NOTUM (0.38) | NOTUMCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL8023032 | 0.73 | NOTUM (0.37) | NOTUMCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL3668228 | 0.73 | NOTUM (0.37) | NOTUMCHRNB2CHRNA3CHRNA4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296603-A | 3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0573975-A1 | 2-alkoxycarbonyl-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0573955-A1 | 3-Amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid derivative and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |