Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425805 | 0.99 | TRPV1 (0.81) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| Tetrahydropiperine SCHEMBL4898699 | 0.91 | TRPV1 (1.00) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| Tetrahydropiperine SCHEMBL29392462 | 0.91 | TRPV1 (1.00) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9426173 | 0.90 | TRPV1 (0.68) | TRPV1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14200777 | 0.90 | TRPV1 (0.97) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL2830225 | 0.86 | TRPV1 (0.64) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4379319 | 0.85 | KMT2A (0.64) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14218026 | 0.84 | TRPV1 (0.61) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL15985215 | 0.84 | TRPV1 (0.61) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4378534 | 0.84 | KMT2A (0.62) | TRPV1ALDH1A1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |