Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960230 | 0.88 | CYP3A4 (0.52) | LMNACYP3A4TDP1L3MBTL1TBXAS1 | |
| SCHEMBL9425314 | 0.83 | RARB (0.54) | CA1CA2CYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6365625 | 0.81 | CA1 (0.66) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL14786695 | 0.79 | MAPT (0.58) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL9425628 | 0.77 | RARB (0.61) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL11506065 | 0.77 | CA12 (0.59) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL19864383 | 0.76 | CYP1A2 (0.54) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL16664035 | 0.76 | CA1 (0.54) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL11486248 | 0.75 | CA12 (0.58) | CA12CA1CA2ESR1CA7 | |
| SCHEMBL18400673 | 0.75 | LMNA (0.61) | CA12CA1CA2ESR1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5349105-A | Skin disorder | ALLERGAN, INC. (US) | 1994-09-20 | — | — | US | disclosed |
| US-5202471-A | Skin disorders | ALLERGAN, INC. (US) | 1993-04-13 | — | — | US | disclosed |