Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123377 | 0.86 | MPL (0.78) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL30098566 | 0.86 | MPL (0.78) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL175806 | 0.85 | KMT2A (0.78) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL1180600 | 0.85 | MPL (0.65) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL1247817 | 0.84 | MPL (1.00) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL2045987 | 0.83 | MPL (0.97) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL2045985 | 0.83 | MPL (0.97) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9425181 | 0.82 | MPL (1.00) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5815835 | 0.82 | MEN1 (0.64) | MPLMEN1KMT2AKDM4EMAPT | |
| SCHEMBL2045986 | 0.82 | MPL (0.76) | MPLMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59197043-A | — | — | None | — | — | JP | disclosed |
| US-5302753-A | Photosensitivity to red and near infrared wavelengths | XEROX CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
| US-5130443-A | Process for the preparation of anilides | XEROX CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| JP-S59197043-A | ELECTROPHOTOGRAPHIC SENSITIVE BODY | RICOH CO LTD | 1984-11-08 | — | — | JP | disclosed |