Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | ATG7 | O95352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427098 | 0.76 | CA1 (0.50) | CA9CA2CA1CA7CA12 | |
| SCHEMBL3823139 | 0.72 | CDK1 (0.38) | CA9CA2CA1CA7CA12 | |
| SCHEMBL9741879 | 0.71 | MAP3K7 (0.40) | CA9CA2CA1CA7CA12 | |
| SCHEMBL10731953 | 0.70 | CA1 (0.47) | CA9CA2CA1CA7CA12 | |
| SCHEMBL1131655 | 0.67 | CA12 (0.47) | CA9CA2CA1CA7CA12 | |
| SCHEMBL9427605 | 0.67 | TRPV4 (0.40) | CA2CA1CA7CA12ATG7 | |
| SCHEMBL9741092 | 0.67 | CA1 (0.45) | CA9CA2CA1CA7CA12 | |
| SCHEMBL9741500 | 0.66 | CA1 (0.41) | CA9CA2CA1CA7CA12 | |
| SCHEMBL9742875 | 0.66 | MAP3K7 (0.36) | CA9CA2CA1MAPT | |
| SCHEMBL6270505 | 0.66 | CDK1 (0.47) | CDK1CDK2CCNB1MGMTCCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298480-A | Plant growth regulators | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1994-03-29 | — | — | US | disclosed |
| WO-1993010103-A1 | HERBICIDAL SULFONYLURIA DERIVATIVES | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1993-05-27 | — | — | WO | disclosed |
| EP-0457581-A1 | Herbicidal sulfonylurea derivatives | ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) | 1991-11-21 | — | — | EP | disclosed |