Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95095 | 0.85 | AR (0.60) | ARMME | |
| SCHEMBL94401 | 0.83 | AR (0.60) | ARMMEALDH1A1LMNA | |
| SCHEMBL94502 | 0.82 | AR (0.76) | ARMMEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL440793 | 0.79 | AR (0.72) | ARMMEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL96572 | 0.76 | AR (0.64) | ARMMEALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL95670 | 0.75 | MME (0.53) | ARMME | |
| SCHEMBL438874 | 0.74 | AR (0.64) | ARMMESMN1; SMN2MAPT | |
| SCHEMBL95396 | 0.74 | AR (1.00) | ARMME | |
| SCHEMBL94639 | 0.73 | AR (0.60) | ARMME | |
| SCHEMBL94638 | 0.73 | AR (0.60) | ARMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | claimed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | claimed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20120065231-A1 | THIOPHENE DERIVATIVE | SUMITOMO CHEMICAL COMPANY LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| EP-2426117-A1 | THIOPHENE DERIVATIVE | Sumitomo Chemical Company, Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065231-A1 | THIOPHENE DERIVATIVE | AR, NR5A1, SHBG | AR 1/4885MME 1367/4885ALDH1A1 729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.