Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.52 |
| ▸ | HCN4 | Q9Y3Q4 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18755247 | 0.87 | BRD4 (0.49) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL334046 | 0.83 | BRD4 (0.60) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL17626791 | 0.82 | BRD4 (0.48) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| Hydrochloric Acid SCHEMBL14696911 | 0.81 | BRD4 (0.47) | BRD4HCN4CCL2HTR1ACHRM2 | |
| SCHEMBL9427617 | 0.81 | BRD4 (0.52) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL15858417 | 0.81 | BRD4 (0.63) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL18870119 | 0.80 | BRD4 (0.64) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL15858418 | 0.80 | BRD4 (0.64) | BRD4HCN4GAASMN1; SMN2CCL2 | |
| SCHEMBL10852154 | 0.79 | BRD4 (0.49) | BRD4HCN4SMN1; SMN2HTR1ASLC6A4 | |
| SCHEMBL2820668 | 0.79 | BRD4 (0.63) | BRD4HCN4GAASMN1; SMN2CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296482-A | (Benzocycloalkyl) alkylamines | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |