Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KCNN2 | Q9H2S1 | 4/20 | 0.38 |
| ▸ | KCNN3 | Q9UGI6 | 4/20 | 0.38 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427543 | 0.96 | HCN4 (0.64) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| SCHEMBL9427426 | 0.90 | HCN4 (0.76) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| SCHEMBL9427641 | 0.87 | HCN4 (0.83) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| SCHEMBL10846943 | 0.84 | HCN4 (0.72) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| SCHEMBL12319782 | 0.84 | HCN4 (0.71) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| SCHEMBL10851789 | 0.82 | HCN4 (0.64) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| Hydrochloric Acid SCHEMBL10848530 | 0.81 | HCN4 (0.63) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| Ivabradine SCHEMBL5163239 | 0.81 | HCN4 (1.00) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| Ivabradine SCHEMBL333201 | 0.81 | HCN4 (1.00) | HCN4SLC6A4CHRM2HTR1ADRD3 | |
| Ivabradine SCHEMBL23472 | 0.81 | HCN4 (1.00) | HCN4SLC6A4CHRM2HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296482-A | (Benzocycloalkyl) alkylamines | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |