Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061913 | 0.92 | HCN4 (0.61) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL14696925 | 0.89 | GAA (0.68) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL10846943 | 0.88 | HCN4 (0.72) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL15980993 | 0.85 | GAA (0.62) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL9427426 | 0.85 | HCN4 (0.76) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL14685025 | 0.85 | HCN4 (0.53) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL9032662 | 0.84 | GAA (0.61) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL30081993 | 0.84 | GAA (0.61) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL14696959 | 0.84 | GAA (0.61) | HCN4MAPTSLC6A4CYP3A4ALOX15 | |
| SCHEMBL9427588 | 0.84 | HCN4 (0.68) | HCN4MAPTSLC6A4CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781509-B2 | New polymorph of ivabradine hydrochloride and method for its preparation | CHEMO RES S L (ES) | 2023-06-14 | — | — | EP | disclosed |
| EP-3140287-B1 | NEW IVABRADINE SALT AND ITS PREPARATION PROCESS | SERVIER LAB (FR) | 2018-03-07 | — | — | EP | disclosed |
| EP-2726462-B1 | ACETONE SOLVATE OF IVABRADINE HYDROCHLORIDE | SANDOZ AG (CH) | 2017-03-22 | — | — | EP | disclosed |
| WO-2011104723-A2 | ACID ADDITION SALTS OF IVABRADINE AND PREPARATION THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2011-09-01 | — | — | WO | disclosed |