Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAT1 | P18440 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427958 | 1.00 | MAPT (0.39) | MAPTKMT2APOLBALDH1A1TDP1 | |
| SCHEMBL9429104 | 0.83 | NAT1 (0.51) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL9429106 | 0.83 | NAT1 (0.51) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL9428029 | 0.82 | NAT1 (0.52) | MAPTKMT2APOLBALDH1A1TDP1 | |
| SCHEMBL9428035 | 0.82 | NAT1 (0.52) | MAPTKMT2APOLBALDH1A1TDP1 | |
| SCHEMBL8534268 | 0.75 | PTGS2 (0.55) | KMT2AALDH1A1MEN1NAT1PTGS1 | |
| SCHEMBL8534273 | 0.75 | PTGS2 (0.55) | KMT2AALDH1A1MEN1NAT1PTGS1 | |
| SCHEMBL8992131 | 0.71 | PTGS2 (0.48) | MAPTKMT2APOLBALDH1A1TDP1 | |
| SCHEMBL8895623 | 0.71 | PTGS2 (0.48) | MAPTKMT2APOLBALDH1A1TDP1 | |
| SCHEMBL9428425 | 0.71 | PTGS2 (0.56) | MAPTKMT2APOLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270319-A | 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-12-14 | — | — | US | claimed |
| WO-1993005039-A1 | 5-HYDROXY-2-PYRIMIDINYLMETHYLENE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-18 | — | — | WO | claimed |
| US-5348957-A | Gastrointestinal ulcer treatment | WARNER-LAMBERT COMPANY (US) | 1994-09-20 | — | — | US | disclosed |
| US-5270319-A | 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-12-14 | — | — | US | disclosed |
| WO-1993005039-A1 | 5-HYDROXY-2-PYRIMIDINYLMETHYLENE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-03-18 | — | — | WO | disclosed |