Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427810 | 0.84 | CYP3A4 (0.41) | PDE4BPDE4DALDH1A1MAPTHTT | |
| SCHEMBL2860220 | 0.76 | KMT2A (0.41) | PDE4BPDE4DPDE4APDE4CIGF1R | |
| SCHEMBL874733 | 0.71 | NQO2 (0.48) | PDE4BPDE4DPDE4APDE4CIGF1R | |
| SCHEMBL27946839 | 0.69 | ALDH1A1 (0.48) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL7497902 | 0.69 | NT5E (0.50) | IGF1RGAAALDH1A1TSHRNFKB1 | |
| SCHEMBL26919067 | 0.69 | CYP3A4 (0.40) | PDE4BPDE4DALDH1A1TSHRMAPT | |
| SCHEMBL11156508 | 0.68 | GAA (0.57) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL30154464 | 0.67 | GAA (0.68) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL586214 | 0.67 | GAA (0.68) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL14856369 | 0.66 | GAA (0.62) | GAAALDH1A1TSHRNFKB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359076-A | Cyclic aminophenylacetic acid derivatives, process for preparing the same and immune response modulator having the same as an effective ingredient | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0538477-A1 | NOVEL CYCLIC AMINOPHENYLACETIC ACID DERIVATIVE, PRODUCTION THEREOF, AND IMMUNE RESPONSE MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |