SCHEMBL9428173

SCHEMBL9428173

CCN(CC1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1)c1cc(C)cc(C)n1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PDE4A P27815 1/20 0.47
PDE3A Q14432 1/20 0.47
TTPA P49638 3/20 0.40
ALOX5 P09917 3/20 0.40
GSTO1 P78417 2/20 0.37
PTPN1 P18031 1/20 0.37
PSEN1 P49768 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9314002 0.92 MEN1 (0.47) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9312785 0.90 MEN1 (0.54) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9314073 0.90 MEN1 (0.45) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9427821 0.88 AKT1 (0.33) MEN1KMT2APDE4APDE3AGSTO1
SCHEMBL9428182 0.85 USP2 (0.44) MEN1KMT2ATTPAALOX5
SCHEMBL9428067 0.82 TTPA (0.46) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9428308 0.80 MEN1 (0.42) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9314113 0.80 MEN1 (0.52) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9314076 0.80 MEN1 (0.44) MEN1KMT2APDE4APDE3ATTPA
SCHEMBL9427380 0.79 TTPA (0.46) MEN1KMT2APDE4APDE3ATTPA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5290797-A Benzopyran compounds ADIR ET COMPAGNIE (FR) 1994-03-01 US disclosed