Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680080 | 0.70 | KMT2A (0.64) | KMT2APOLBALDH1A1HSD17B10GPR3 | |
| SCHEMBL3066757 | 0.70 | ALOX5 (0.54) | ALOX5KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL9721073 | 0.69 | — | — | |
| SCHEMBL29450289 | 0.68 | ALOX5 (1.00) | ALOX5KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL291774 | 0.68 | ALOX5 (1.00) | ALOX5KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL14041182 | 0.68 | ALOX5 (0.52) | ALOX5KMT2APOLBALDH1A1HSD17B10 | |
| SCHEMBL2514438 | 0.67 | KDM4E (0.63) | KMT2AALDH1A1HSD17B10GPR3MAPT | |
| SCHEMBL31414202 | 0.67 | KMT2A (1.00) | KMT2AALDH1A1HSD17B10GPR3PSMB8 | |
| SCHEMBL3063883 | 0.67 | KMT2A (1.00) | KMT2AALDH1A1HSD17B10GPR3PSMB8 | |
| SCHEMBL31414198 | 0.67 | KMT2A (1.00) | KMT2AALDH1A1HSD17B10GPR3PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342937-A | Extraction of metals especially gallium | ZENECA, LIMITED (GB) | 1994-08-30 | — | — | US | claimed |
| EP-0408203-A2 | Heterocyclic thione | ZENECA LIMITED (GB) | 1991-01-16 | — | — | EP | claimed |
| US-5342937-A | Extraction of metals especially gallium | ZENECA, LIMITED (GB) | 1994-08-30 | — | — | US | disclosed |
| US-5074911-A | Extracting metal values from aqueous solution with immiscible solvent and dissolved heterocyclic thione | IMPERICAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-24 | — | — | US | disclosed |
| EP-0408203-A2 | Heterocyclic thione | ZENECA LIMITED (GB) | 1991-01-16 | — | — | EP | disclosed |