Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.44 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 6/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13225912 | 0.84 | GBA2 (0.42) | ECE1GBA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5412971 | 0.78 | ECE1 (0.43) | ECE1GBA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL31629521 | 0.76 | SMN1; SMN2 (0.54) | ECE1GBA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5407269 | 0.75 | ECE1 (0.52) | ECE1LMNAPOLBALDH1A1BCHE | |
| SCHEMBL5410369 | 0.75 | ECE1 (0.43) | ECE1OPRK1HRH2HRH1HTR2C | |
| SCHEMBL856258 | 0.74 | POLB (0.43) | GBA2LMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28230068 | 0.74 | GBA2 (0.55) | ECE1GBA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5401467 | 0.74 | ECE1 (0.43) | ECE1GBA2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5422520 | 0.74 | TBXAS1 (0.43) | ECE1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7800300 | 0.74 | P2RX4 (0.42) | POLBSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317016-A | Pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-31 | — | — | US | disclosed |