Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428628 | 1.00 | KEAP1 (0.50) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL9429206 | 0.93 | KEAP1 (0.47) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL9429200 | 0.93 | KEAP1 (0.47) | KEAP1NFE2L2HRH1MAOBBCHE | |
| Oxalic Acid SCHEMBL9429434 | 0.93 | KEAP1 (0.46) | KEAP1NFE2L2HRH1MAOBBCHE | |
| Oxalic Acid SCHEMBL9429427 | 0.93 | KEAP1 (0.46) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL9428778 | 0.92 | MAOB (0.50) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL30383471 | 0.92 | MAOB (0.50) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL9428775 | 0.92 | MAOB (0.50) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL9429068 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2HRH1MAOBBCHE | |
| SCHEMBL30383723 | 0.92 | KEAP1 (0.46) | KEAP1NFE2L2HRH1MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |