SCHEMBL9428639

SCHEMBL9428639

CCCCCCCCCCCCCCCCCCON1C(C)(C)CC(C(CCC)Nc2nc(Cl)nc(NC(CCC)C3CC(C)(C)N(OCCCCCCCCCCCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.35
ALDH1A1 P00352 1/20 0.31
IDH1 O75874 1/20 0.30
IDH2 P48735 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7456205 1.00 KMT2A (0.35) KMT2AALDH1A1IDH1IDH2
SCHEMBL3268721 0.98 KMT2A (0.33) KMT2A
SCHEMBL3260642 0.97 KMT2A (0.31) KMT2A
SCHEMBL9429497 0.95 KMT2A (0.44) KMT2AALDH1A1
SCHEMBL7475738 0.94
SCHEMBL8649932 0.90
SCHEMBL9428791 0.89
SCHEMBL9428528 0.89 CDK1 (0.30)
SCHEMBL692773 0.89 ALDH1A1 (0.31) ALDH1A1IDH1IDH2
SCHEMBL599959 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300544-A Non-migrating 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperdine 1,3,5-triazine derivatives as polymer stabilizers CIBA-GEIGY CORPORATION (US) 1994-04-05 US disclosed
US-5216156-A Stabilizers having functional groups which chemically bond with polymer substrates CIBA-GEIGY CORPORATION (US) 1993-06-01 US disclosed