SCHEMBL9428735

SCHEMBL9428735

C=CCOC(=O)CCCC=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
ALDH1A1 P00352 3/20 0.46
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.41
PKM P14618 1/20 0.41
EPHX2 P34913 1/20 0.40
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 1/20 0.39
CYP3A4 P08684 2/20 0.36
NR1I2 O75469 1/20 0.36
PGR P06401 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PTGS2 P35354 1/20 0.36
PDE4D Q08499 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HIF1A Q16665 1/20 0.35
MAPT P10636 4/20 0.34
CACNA1B Q00975 1/20 0.34
APBA1 Q02410 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3887514 0.94 TSHR (0.62) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL10632862 0.92 TSHR (0.66) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL7205385 0.92 TSHR (0.66) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL9719094 0.88 TSHR (0.53) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL6050165 0.88 TSHR (0.63) TSHRALDH1A1GAASMN1; SMN2PKM
Hydrochloric Acid SCHEMBL30639520 0.86 TSHR (0.52) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL153651 0.85 TSHR (0.77) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL463195 0.85 TSHR (0.70) TSHRALDH1A1GAASMN1; SMN2PKM
Formic Acid SCHEMBL27747307 0.83 TSHR (0.69) TSHRALDH1A1GAASMN1; SMN2PKM
SCHEMBL180289 0.83 TSHR (0.81) TSHRALDH1A1GAASMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
US-5314918-A Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1994-05-24 US disclosed
EP-0548291-A1 PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS SMITHKLINE BEECHAM CORPORATION (US) 1993-06-30 EP disclosed
EP-0358240-B1 INTERMEDIATES FOR THE PREPARATION OF LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-06-09 EP disclosed
EP-0532674-A4 LEUKOTRIENE ANTAGONISTS 1993-04-07 EP disclosed
EP-0532674-A1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1993-03-24 EP disclosed
US-5143931-A 2-Phenyl-2((tetrazolyl or imidazolyl)thio)alkanoic acid derivatives; antiphylactic and bronchodilator agents SMITHKLINE BEECHAM CORPORATION (US) 1992-09-01 US disclosed
EP-0296731-B1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1992-08-26 EP disclosed
US-5135938-A Bronchodilator SMITHKLINE BEECHAM CORPORATION (US) 1992-08-04 US disclosed
WO-1992005156-A1 PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS SMITHKLINE BEECHAM CORPORATION (US) 1992-04-02 WO disclosed
EP-0202759-B1 LEUKOTRIENE ANTAGONISTS SMITHKLINE BEECHAM CORPORATION (US) 1990-06-20 EP disclosed
EP-0358240-A2 Intermediates for the preparation of leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1990-03-14 EP disclosed
US-4874792-A RESPIRATORY SYSTEM DISORDERS SMITHKLINE BECKMAN CORPORATION (US) 1989-10-17 US disclosed
EP-0313697-A1 Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1989-05-03 EP disclosed
US-4820719-A ANTIALLERGENS, ANTIINFLAMMATORY, ANTIISCHEMIC AND HYPOTENSIVE AGENTS SMITHKLINE BECKMAN CORPORATION (US) 1989-04-11 US disclosed
EP-0296731-A1 Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1988-12-28 EP disclosed
EP-0296732-A1 Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1988-12-28 EP disclosed
US-4769386-A Imidazolylthioalkenoic acids and -alkenols and leukotriene antagonistic composition containing them SMITHKLINE BECKMAN CORPORATION (US) 1988-09-06 US disclosed
EP-0202759-A2 Leukotriene antagonists SMITHKLINE BEECHAM CORPORATION (US) 1986-11-26 EP disclosed
EP-0168950-A1 Leukotriene antagonists SMITHKLINE BECKMAN CORPORATION (US) 1986-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11822247-B2 Material for forming organic film, method for forming organic film, patterning process, and compound EPCAM, CDH1, DNMT3L TSHR 4764/4885ALDH1A1 2511/4885GAA 4434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.