Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795032 | 1.00 | ECE1 (0.31) | ECE1 | |
| SCHEMBL9519269 | 0.83 | MAPT (0.31) | — | |
| SCHEMBL10702205 | 0.83 | MAPT (0.31) | — | |
| SCHEMBL7805556 | 0.82 | ECE1 (0.34) | ECE1 | |
| SCHEMBL9794941 | 0.81 | ECE1 (0.41) | ECE1 | |
| SCHEMBL9204827 | 0.80 | SIGMAR1 (0.33) | ECE1 | |
| SCHEMBL9429298 | 0.80 | — | — | |
| SCHEMBL9520725 | 0.79 | MAPT (0.34) | — | |
| SCHEMBL9429313 | 0.78 | ECE1 (0.34) | ECE1 | |
| SCHEMBL10518904 | 0.75 | CYP19A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306816-A | Processes for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0499196-A1 | Intermediates and process for preparing carbapenem derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-19 | — | — | EP | disclosed |
| US-4983596-A | Microbiocides; for treatment of infectious diseases | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-01-08 | — | — | US | disclosed |
| EP-0341557-A1 | 3-pyrrolidinylthio-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |