Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | PAM | P19021 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL5994259 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| Hexane SCHEMBL2349171 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL5448566 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL1645398 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL6443707 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL454 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL8375548 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| Hexane SCHEMBL3138126 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| SCHEMBL116995 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 | |
| Hexane SCHEMBL3151787 | 0.94 | DGKA (0.75) | DGKAPAMTSHRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299279-B | Substituted arylaminol compounds, methods of making, and uses thereof | 北京梅尔森医药技术开发有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-108299279-A | Substituted aryl amine alcohol compound and its preparation method and application | 北京梅尔森医药技术开发有限公司 | 2018-07-20 | — | — | CN | disclosed |
| US-5336622-A | Competitive binding using a fluorescent dye tracer; monitoring dosage in biological fluid; sensitivity; accuracy; efficiency | ABBOTT LABORATORIES (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0242847-B1 | TRACERS FOR USE IN FLECAINIDE FLUORESCENCE POLARIZATION IMMUNOASSAY | ABBOTT LABORATORIES (US) | 1993-06-02 | — | — | EP | disclosed |
| EP-0242847-A2 | Tracers for use in flecainide fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4345096-A | 3-/P-OXYPHENYLALKYL/GLUTARIC ACID | E. R. SQUIBB & SONS, INC. (US) | 1982-08-17 | — | — | US | disclosed |
| US-4230621-A | TRACERS, HYDROXYPHENYLGLUTARIC ACID DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4221725-A | CHEMICAL INTERMEDIATE | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |
| US-4001249-A | CYCLOCOUPLING N-ACYLPYRROLE AND A,A*-HALOGENOKETONE, REDUCING AGENTS | SANWA KAGAKU KENKYUSHO CO. LTD. (JA) | 1977-01-04 | — | — | US | disclosed |
| US-3997325-A | (Alkynyloxy)alkyl and (alkenyloxy)alkyl carbamates and their use as herbicides | AMERICAN CYANAMID COMPANY (US) | 1976-12-14 | — | — | US | disclosed |