Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856273 | 0.90 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1HPGDKMT2ALMNA | |
| SCHEMBL9855528 | 0.88 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1LNPEPHPGDKMT2A | |
| SCHEMBL9429049 | 0.87 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1HPGDKMT2ALMNA | |
| SCHEMBL9428630 | 0.87 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1HPGDKMT2ALMNA | |
| SCHEMBL9363995 | 0.83 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1HIF1AHPGDLMNA | |
| SCHEMBL9428579 | 0.83 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1HPGDKMT2ALMNA | |
| SCHEMBL10436576 | 0.81 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1HPGDKMT2ALMNA | |
| SCHEMBL9484022 | 0.81 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1KMT2AL3MBTL1FAAH | |
| SCHEMBL9429346 | 0.81 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1LNPEPLMNAFAAH | |
| SCHEMBL9364032 | 0.80 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1KMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314918-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-05-24 | — | — | US | disclosed |
| EP-0296732-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0403249-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0296732-A1 | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1988-12-28 | — | — | EP | disclosed |