Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429151 | 0.88 | FABP4 (0.50) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428337 | 0.81 | FABP4 (0.73) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428386 | 0.72 | FABP4 (0.68) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428414 | 0.72 | KDM4E (0.55) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9430036 | 0.71 | FABP4 (0.43) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428471 | 0.69 | FABP4 (0.50) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428176 | 0.69 | FABP4 (0.49) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9429123 | 0.68 | KDM4E (0.53) | FABP4PTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL9428927 | 0.66 | KDM4E (0.41) | FABP4KDM4EHPGDRXRARXRB | |
| SCHEMBL9428317 | 0.65 | FABP4 (1.00) | FABP4PTGIRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348969-A | Oxazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-09-20 | — | — | US | claimed |
| US-5348969-A | Oxazole derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-09-20 | — | — | US | disclosed |