Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 6/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148425 | 0.91 | SRD5A1 (0.64) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9369249 | 0.89 | OXER1 (0.48) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9153190 | 0.88 | SRD5A1 (0.64) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9374844 | 0.88 | OXER1 (0.48) | SRD5A1SRD5A2OXER1HDAC3HDAC1 | |
| SCHEMBL9156270 | 0.88 | SRD5A1 (0.63) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9372909 | 0.87 | OXER1 (0.50) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9149126 | 0.86 | SRD5A1 (0.62) | SRD5A1SRD5A2OXER1KDM4EALOX5AP | |
| SCHEMBL9150072 | 0.85 | SRD5A2 (0.52) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9538732 | 0.84 | SRD5A2 (0.49) | SRD5A1SRD5A2OXER1KDM4EHPGD | |
| SCHEMBL9369182 | 0.84 | SRD5A1 (0.54) | SRD5A1SRD5A2OXER1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283251-A | Testosterone 5a-reductase inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-02-01 | — | — | US | disclosed |