Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 9/20 | 0.52 |
| ▸ | MPC2 | O95563 | 2/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430681 | 0.83 | FFAR1 (0.48) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL9429648 | 0.83 | FFAR1 (0.48) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL9429683 | 0.82 | PPARG (0.56) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL8182679 | 0.77 | PTPN1 (0.79) | PTPN1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL9429707 | 0.76 | IGF1R (0.59) | MEN1HPGDKMT2A | |
| SCHEMBL19828508 | 0.75 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL19217579 | 0.75 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL2608677 | 0.75 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9CYP3A4 | |
| SCHEMBL3840336 | 0.75 | FFAR1 (0.65) | PTPN1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL8310673 | 0.74 | FFAR1 (0.63) | PPARGMPC2CYP2C8CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | disclosed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | disclosed |