Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | CYCS | P99999 | 2/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951397 | 0.91 | STAT3 (0.54) | STAT3STAT1ABCG2GAAKDM4E | |
| SCHEMBL5576182 | 0.85 | STAT3 (0.51) | STAT3STAT1ABCG2GAAKDM4E | |
| SCHEMBL8189718 | 0.84 | STAT3 (0.49) | STAT3STAT1ABCG2MGAMGAA | |
| SCHEMBL8189722 | 0.84 | STAT3 (0.49) | STAT3STAT1ABCG2MGAMGAA | |
| SCHEMBL2950389 | 0.83 | STAT3 (0.54) | STAT3STAT1ABCG2GAAKDM4E | |
| SCHEMBL9590030 | 0.83 | STAT3 (0.60) | STAT3STAT1ABCG2KDM4EMAPT | |
| SCHEMBL9429841 | 0.82 | MGAM (0.39) | STAT3STAT1MGAMGAASI | |
| SCHEMBL8996959 | 0.82 | STAT3 (0.59) | STAT3STAT1ABCG2KDM4EMAPT | |
| SCHEMBL5319095 | 0.81 | STAT3 (0.64) | STAT3STAT1ABCG2TOP1TERT | |
| SCHEMBL30205816 | 0.81 | STAT3 (0.64) | STAT3STAT1ABCG2TOP1TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284647-A | Administering for magnetic resonance imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |