Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189718 | 0.93 | STAT3 (0.49) | STAT3STAT1GAAMGAMSI | |
| SCHEMBL8186763 | 0.88 | ABCG2 (0.49) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL5576182 | 0.87 | STAT3 (0.51) | STAT3STAT1GAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8187553 | 0.86 | ABCG2 (0.48) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL2951397 | 0.86 | STAT3 (0.54) | STAT3STAT1GAAKDM4EMEN1 | |
| SCHEMBL9429844 | 0.84 | STAT3 (0.52) | STAT3STAT1GAAMGAMSI | |
| SCHEMBL14350953 | 0.83 | ABCG2 (0.48) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL2950389 | 0.79 | STAT3 (0.54) | STAT3STAT1GAAKDM4EMEN1 | |
| SCHEMBL9590030 | 0.78 | STAT3 (0.60) | STAT3STAT1KDM4EALDH1A1MAPT | |
| SCHEMBL4266558 | 0.78 | STAT3 (0.63) | STAT3STAT1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6087493-A | ENZYME IHIBITORS | REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0988037-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998033503-A1 | PORPHYRIN COMPOUNDS AS TELOMERASE INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-08-06 | — | — | WO | disclosed |