Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 6/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 14/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429804 | 0.95 | LTB4R2 (0.43) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9430124 | 0.91 | LTB4R2 (0.49) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9430059 | 0.90 | LTB4R2 (0.48) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9430102 | 0.86 | AGTR1 (0.45) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL3087 | 0.86 | AGTR1 (0.55) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9430064 | 0.85 | LTB4R2 (0.46) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9429098 | 0.85 | LTB4R2 (0.54) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL9429201 | 0.85 | LTB4R2 (0.50) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL3127151 | 0.83 | LTB4R2 (0.49) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL8472415 | 0.83 | AGTR1 (0.43) | LTB4R2AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369110-A | Hypotensive agents, cardiac insufficiency treatment | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | claimed |
| EP-0490820-A2 | Biphenylyl compounds | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | claimed |
| US-5369110-A | Hypotensive agents, cardiac insufficiency treatment | CIBA-GEIGY CORPORATION (US) | 1994-11-29 | — | — | US | disclosed |
| EP-0490820-A2 | Biphenylyl compounds | CIBA-GEIGY AG (CH) | 1992-06-17 | — | — | EP | disclosed |