Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 7/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971189 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL2759892 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL14611674 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL2759893 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL11303853 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL12676448 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL14155064 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL4649867 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL21806974 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 | |
| SCHEMBL27971187 | 1.00 | CES2 (0.56) | CES2POLBBLMGMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107835800-A | cyclic compound | 武田药品工业株式会社 | 2018-03-23 | — | — | CN | disclosed |
| US-5362878-A | Intermediates for making N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) | PFIZER INC. (US) | 1994-11-08 | — | — | US | disclosed |