SCHEMBL943003

SCHEMBL943003

Cc1cccc(CNCc2cccc(C)n2)n1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.64
KDM1A O60341 1/20 0.50
MAOA P21397 1/20 0.50
MAOB P27338 1/20 0.50
CCR1 P32246 1/20 0.46
CCR8 P51685 1/20 0.46
NPSR1 Q6W5P4 2/20 0.44
NOS3 P29474 1/20 0.43
NOS2 P35228 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
P2RX7 Q99572 1/20 0.41
HDAC6 Q9UBN7 2/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
CXCR4 P61073 1/20 0.40
HSD17B10 Q99714 1/20 0.40
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1038536 0.90 SMN1; SMN2 (0.58) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL9777407 0.90 SMN1; SMN2 (0.68) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL25376464 0.89 SMN1; SMN2 (0.71) SMN1; SMN2KDM1AMAOAMAOBMEN1
SCHEMBL13197295 0.87 SMN1; SMN2 (0.56) SMN1; SMN2KDM1AMAOAMAOBMEN1
SCHEMBL9777453 0.86 SMN1; SMN2 (0.64) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL22564633 0.86 SMN1; SMN2 (0.64) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL2258317 0.85 SMN1; SMN2 (0.62) SMN1; SMN2KDM1AMAOAMAOBNPSR1
SCHEMBL10483914 0.85 SMN1; SMN2 (0.62) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL29791992 0.84 SMN1; SMN2 (0.53) SMN1; SMN2KDM1AMAOAMAOBCCR1
SCHEMBL2476858 0.84 SMN1; SMN2 (0.53) SMN1; SMN2KDM1AMAOAMAOBCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513260-B2 Pyrazinylpyrazoles BAYER CROPSCIENCE AG (DE) 2013-08-20 US claimed
EP-2435420-B1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG (DE) 2013-04-03 EP claimed
US-20120190687-A1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG 2012-07-26 US claimed
US-20110021539-A1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG (DE) 2011-01-27 US claimed
WO-2010136145-A1 PYRAZINYLPYRAZOLES BAYER CROPSCIENCE AG (DE) 2010-12-02 WO claimed
CN-118930696-A Nitrogen-containing heterocyclic resin, preparation method and application thereof 上海稀固科技有限公司 2024-11-12 CN disclosed
US-10184052-B2 Near infrared radiation-absorbing composition, near infrared radiation cut-off filter and production method therefor, and camera module and production method therefor FUJIFILM CORPORATION (JP) 2019-01-22 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
EP-2435420-B1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG (DE) 2013-04-03 EP disclosed
US-20120190687-A1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG 2012-07-26 US disclosed
WO-2012084852-A2 ECTOPARASITICIDAL ACTIVE SUBSTANCE COMBINATIONS BAYER ANIMAL HEALTH GMBH (DE) 2012-06-28 WO disclosed
US-20110021539-A1 Pyrazinylpyrazoles BAYER CROPSCIENCE AG (DE) 2011-01-27 US disclosed
EP-2266973-A1 Pyrazinylpyrazole Bayer CropScience AG (DE) 2010-12-29 EP disclosed
WO-2010136145-A1 PYRAZINYLPYRAZOLES BAYER CROPSCIENCE AG (DE) 2010-12-02 WO disclosed
US-7696245-B2 Fluorescent probe for zinc SEKISUI MEDICAL CO., LTD. (JP) 2010-04-13 US disclosed
US-7696245-B2 Fluorescent probe for zinc SEKISUI MEDICAL CO., LTD. (JP) 2010-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110021539-A1 Pyrazinylpyrazoles CYP4F3, CYP4B1, CYP1A2 SMN1; SMN2 2333/4885KDM1A 2742/4885MAOA 2603/4885
US-20120190687-A1 Pyrazinylpyrazoles CYP4F3, CYP4B1, CYP1A2 SMN1; SMN2 2333/4885KDM1A 2742/4885MAOA 2603/4885
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 SMN1; SMN2 2133/4885KDM1A 1109/4885MAOA 2578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.