SCHEMBL9430205

SCHEMBL9430205

O=C1CC(=O)OC(CCl)C1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018500 0.79
SCHEMBL371927 0.79
SCHEMBL10018502 0.79
SCHEMBL8780196 0.70 CYP1A2 (0.60) ALDH1A1
SCHEMBL18919592 0.70 CYP1A2 (0.60) ALDH1A1
SCHEMBL4472556 0.68
SCHEMBL4490657 0.68
SCHEMBL4472560 0.68
SCHEMBL7073737 0.68
SCHEMBL798189 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292891-A Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same and method for preparing optically active compound for synthesis of physiologically active substance and optically active intermediate compound CHISSO CORPORATION (JP) 1994-03-08 US claimed
US-5292891-A Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same and method for preparing optically active compound for synthesis of physiologically active substance and optically active intermediate compound CHISSO CORPORATION (JP) 1994-03-08 US disclosed
US-5292891-A Optically active 2,2-dimethyl-1,3-dioxin-4-ones and method for preparing same and method for preparing optically active compound for synthesis of physiologically active substance and optically active intermediate compound CHISSO CORPORATION (JP) 1994-03-08 US disclosed