Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207801 | 0.79 | IDO1 (0.43) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL9664457 | 0.79 | KCNH2 (0.46) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL8532241 | 0.79 | IDO1 (0.43) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL6207806 | 0.79 | IDO1 (0.43) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL9664449 | 0.79 | KCNH2 (0.46) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2096033 | 0.77 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2096029 | 0.77 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2091740 | 0.77 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL10805006 | 0.77 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL10805012 | 0.77 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358955-A | Antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-10-25 | — | — | US | disclosed |