Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664457 | 1.00 | KCNH2 (0.46) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2091738 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL27645313 | 0.79 | KCNH2 (0.53) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL9430337 | 0.79 | KCNH2 (0.49) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2096033 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2091740 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL10805012 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL2096029 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL10805006 | 0.79 | KCNH2 (0.45) | KCNH2MAOBIDO1AGXTTAAR1 | |
| SCHEMBL3811260 | 0.78 | MAOB (0.75) | KCNH2MAOBIDO1AGXTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134424-B1 | UNSATURATED ARYLALKYL AMMONIUM SALTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | claimed |
| EP-0134424-A1 | Unsaturated arylalkyl ammonium salts | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | claimed |
| EP-0131302-B1 | IMIDAZOLIUM SALTS, INTERMEDIATES THERETO AND THEIR USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| EP-0134424-B1 | UNSATURATED ARYLALKYL AMMONIUM SALTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | disclosed |
| US-4689341-A | Antiarrhythmic imidazoles | SCHERING A.G. (DE) | 1987-08-25 | — | — | US | disclosed |
| US-4613609-A | Antiarrhythmic imidazoliums | SCHERING A. G. (DE) | 1986-09-23 | — | — | US | disclosed |
| US-4581370-A | Antiarrhythmic imidazoliums | SCHERING A.G. (DE) | 1986-04-08 | — | — | US | disclosed |
| US-4545995-A | Substituted phenylalkenyl ammonium salts as antiarrhythimc agents | SCHERING A.G. (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0134424-A1 | Unsaturated arylalkyl ammonium salts | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-03-20 | — | — | EP | disclosed |
| EP-0131302-A2 | Imidazolium salts, intermediates thereto and their use | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-01-16 | — | — | EP | disclosed |