SCHEMBL9430355

SCHEMBL9430355

C=Cc1cccc(O)c1C(=O)OCC

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.72
CA1 P00915 5/20 0.72
CA2 P00918 5/20 0.72
CA7 P43166 5/20 0.72
CA9 Q16790 5/20 0.72
CA14 Q9ULX7 5/20 0.72
NR1H2 P55055 1/20 0.51
NR1H3 Q13133 1/20 0.51
CYP3A4 P08684 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
SIRT5 Q9NXA8 1/20 0.45
MAPT P10636 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HPGD P15428 1/20 0.44
LMNA P02545 3/20 0.44
ALOX12 P18054 1/20 0.44
GAA P10253 2/20 0.44
HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5788019 0.85 CA12 (1.00) CA12CA1CA2CA7CA9
SCHEMBL21052524 0.84 TSHR (0.56) CA12CA1CA2CA7CA9
SCHEMBL13954078 0.82 CA1 (0.69) CA12CA1CA2CA7CA9
SCHEMBL28351195 0.82 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL147754 0.82 CA12 (0.85) CA12CA1CA2CA7CA9
SCHEMBL1131579 0.81 TDP1 (0.55) CA12CA1CA2CA7CA9
SCHEMBL9294987 0.80 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL9294982 0.80 CA12 (0.64) CA12CA1CA2CA7CA9
SCHEMBL9058772 0.79 ALDH1A1 (0.53) CA12CA1CA2CA7CA9
SCHEMBL28351196 0.79 TSHR (0.53) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5360913-A Herbicides and bioregulators for growth BASF AKTIENGESELLSCHAFT (DE) 1994-11-01 US disclosed
US-5201937-A SALICYCLIC ACID DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed