Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.98 |
| ▸ | LTB4R2 | Q9NPC1 | 13/20 | 0.98 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | HTR2B | P41595 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7751099 | 0.99 | LTB4R (1.00) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL9430782 | 0.98 | LTB4R (0.98) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8655402 | 0.98 | LTB4R (0.98) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL9431503 | 0.94 | LTB4R (0.86) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL9431492 | 0.92 | LTB4R (0.86) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8653365 | 0.92 | LTB4R (0.86) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8652398 | 0.91 | LTB4R (0.85) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8651177 | 0.90 | LTB4R (0.83) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL9431167 | 0.89 | NR1H4 (1.00) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 | |
| SCHEMBL8653675 | 0.89 | LTB4R (0.82) | LTB4RLTB4R2NR1H4MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352690-A | For asthma, allergies | ELI LILLY AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |