Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 17/20 | 0.74 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 17/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.71 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430034 | 0.85 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7460178 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL515771 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9430830 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| Ammonia Solution, Strong SCHEMBL10420651 | 0.82 | PDE4A (0.97) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9430425 | 0.82 | PDE4A (0.92) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9649326 | 0.81 | PDE4A (0.90) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL5400933 | 0.79 | PDE4A (0.91) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL3842077 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL21381259 | 0.78 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338741-A | Cardiotonic agents | NESTEC S.A. (CH) | 1994-08-16 | — | — | US | disclosed |