Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430298 | 0.94 | MAOB (0.45) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL9048086 | 0.93 | MAOB (0.56) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL11114770 | 0.86 | MAOB (0.59) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL19068931 | 0.85 | MAOB (0.51) | MAOBL3MBTL1ALOX5LMNACYP1A2 | |
| SCHEMBL3050888 | 0.85 | MAOB (0.58) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL14925312 | 0.84 | PPARD (0.51) | MAOBL3MBTL1MAOARAB9AALOX5 | |
| SCHEMBL9049531 | 0.84 | MAOB (0.44) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL9430862 | 0.83 | MAOB (0.53) | MAOBL3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9315251 | 0.82 | MAOB (0.58) | MAOBL3MBTL1GAAMAPTMAOA | |
| SCHEMBL9431235 | 0.80 | SIRT2 (0.54) | MAOBL3MBTL1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347050-A | Cardioselective adrenoreceptor blocking agents; prophylaxis and therapy for coronary diseases, glaucoma, migraine | BERTHOLD RICHARD (CH) | 1994-09-13 | — | — | US | disclosed |
| EP-0052072-B1 | 3-AMINOPROPOXYPHENYL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANDOZ AG (CH) | 1985-02-20 | — | — | EP | disclosed |