Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ATF4 | P18848 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL943151 | 1.00 | EPHX2 (0.58) | EPHX2MTNR1AMTNR1BLMNASMN1; SMN2 | |
| SCHEMBL224441 | 0.91 | — | — | |
| SCHEMBL9795085 | 0.83 | EPHX2 (0.54) | EPHX2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL9497817 | 0.83 | EPHX2 (0.54) | EPHX2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL854701 | 0.83 | MTNR1A (0.45) | EPHX2MTNR1AMTNR1BLMNASMN1; SMN2 | |
| SCHEMBL854700 | 0.83 | MTNR1A (0.45) | EPHX2MTNR1AMTNR1BLMNASMN1; SMN2 | |
| SCHEMBL4303783 | 0.82 | — | — | |
| SCHEMBL3453982 | 0.82 | SMN1; SMN2 (0.61) | EPHX2LMNASMN1; SMN2KMT2AHPGD | |
| SCHEMBL9797827 | 0.81 | KMT2A (0.59) | EPHX2MTNR1AMTNR1BLMNASMN1; SMN2 | |
| SCHEMBL19706964 | 0.81 | SMYD3 (0.49) | MTNR1AMTNR1BLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |
| US-5411989-A | Cardiovascular disorders | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-05-02 | — | — | US | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |