⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232503 | 0.69 | — | — | |
| SCHEMBL28380427 | 0.67 | — | — | |
| SCHEMBL8767942 | 0.67 | — | — | |
| SCHEMBL4894701 | 0.67 | — | — | |
| SCHEMBL941404 | 0.67 | — | — | |
| SCHEMBL721829 | 0.63 | — | — | |
| SCHEMBL23704655 | 0.61 | — | — | |
| Sulfamate SCHEMBL6474390 | 0.57 | — | — | |
| SCHEMBL4335791 | 0.57 | CA1 (0.50) | — | |
| SCHEMBL7492627 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602731-A | Inhibitors of metalloproteinase | ASTRAZENECA AB (SE) | 2009-12-16 | — | — | CN | claimed |
| CN-1962641-A | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2007-05-16 | — | — | CN | claimed |
| CN-1509275-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| CN-1509286-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| CN-1509273-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| CN-1509276-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | claimed |
| US-8680270-B2 | Metallo-oxidoreductase inhibitors using metal binding moieties in combination with targeting moieties | VIAMET PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| EP-2086546-B1 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | VIAMET PHARMACEUTICALS INC (US) | 2013-07-10 | — | — | EP | disclosed |
| EP-2543368-A1 | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties | Viamet Pharmaceuticals, Inc. (US) | 2013-01-09 | — | — | EP | disclosed |
| CN-1962641-B | Metalloproteinase inhibitors | ASTRAZENECA AB | 2012-07-04 | — | — | CN | disclosed |
| US-20110015158-A1 | METALLOENZYME INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | VIAMET PHARMACEUTICALS, INC. (US) | 2011-01-20 | — | — | US | disclosed |
| US-20100305078-A1 | METALLO-OXIDOREDUCTASE INHIBITORS USING METAL BINDING MOIETIES IN COMBINATION WITH TARGETING MOIETIES | VIAMET PHARMACEUTICALS, INC. (US) | 2010-12-02 | — | — | US | disclosed |
| CN-101602731-A | Inhibitors of metalloproteinase | ASTRAZENECA AB (SE) | 2009-12-16 | — | — | CN | disclosed |
| CN-1962641-A | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2007-05-16 | — | — | CN | disclosed |
| CN-1313448-C | Metalloprotease inhibitors | ASTRAZENECA AB (SE) | 2007-05-02 | — | — | CN | disclosed |
| CN-1269804-C | Metalloprotease inhibitors | ASTRAZENECA AB (SE) | 2006-08-16 | — | — | CN | disclosed |
| CN-1509275-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1509273-A | Metalloproteinase inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1509276-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | disclosed |
| CN-1509286-A | Metalloprotease inhibitors | — | 2004-06-30 | — | — | CN | disclosed |