Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.44 |
| ▸ | SELE | P16581 | 2/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431707 | 0.85 | SLC9A1 (0.42) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL829143 | 0.85 | SLC9A1 (0.60) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9432087 | 0.83 | SLC9A1 (0.49) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11090568 | 0.82 | HDAC3 (0.51) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9431014 | 0.82 | SLC9A1 (0.48) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9431469 | 0.82 | HDAC3 (0.43) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9431460 | 0.82 | HDAC3 (0.43) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL828305 | 0.80 | SLC9A1 (0.60) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9432172 | 0.78 | SLC9A1 (0.42) | SLC9A1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL9431356 | 0.77 | PLAU (0.58) | SLC9A1ICAM1SELEVCAM1F9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340833-A | Antiarthritic, antiinflammatory, antitumor agents | EISAI CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0568289-A2 | Benzothiophenes and thienothiophenes and related compounds useful, for example, as urokinase inhibitors | Eisai Co., Ltd. (JP) | 1993-11-03 | — | — | EP | disclosed |