Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050275 | 0.83 | DRD4 (0.50) | SLC6A2SLC6A4CYP1A2CYP2D6 | |
| SCHEMBL10034629 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4CHRNA7SIRT2CYP2A6 | |
| SCHEMBL6945022 | 0.80 | SLC6A2 (0.63) | SLC6A2SLC6A4CHRNA7SIRT2CYP2A6 | |
| SCHEMBL9432019 | 0.76 | SLC6A2 (0.52) | SLC6A2SLC6A4CHRNA7SIRT2CYP2A6 | |
| SCHEMBL29872178 | 0.72 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRNA7SIRT2CYP2A6 | |
| SCHEMBL8751082 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL8751031 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL4672768 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL8200213 | 0.70 | SLC6A2 (0.58) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL2697459 | 0.70 | SLC6A2 (1.00) | SLC6A2SLC6A4CHRNA7SIRT2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |