Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10034629 | 1.00 | SLC6A2 (0.63) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL9844932 | 0.81 | CHRNA7 (0.49) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL29872178 | 0.80 | SLC6A2 (0.57) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL9432014 | 0.80 | SLC6A2 (0.53) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL7834371 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL8479576 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL7834832 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL9432019 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL8200213 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 | |
| SCHEMBL2697459 | 0.78 | SLC6A2 (1.00) | SLC6A2SLC6A4CHRNA7CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115705-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-07-18 | — | — | EP | claimed |
| EP-0984961-B1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | claimed |
| US-6143751-A | Pyridine derivatives and pharmaceutical compositions containing them | ASTRAZENECA UK LIMITED (GB) | 2000-11-07 | — | — | US | claimed |
| EP-1019375-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-07-19 | — | — | EP | claimed |
| WO-2000018736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-04-06 | — | — | WO | claimed |
| EP-0984961-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-03-15 | — | — | EP | claimed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | claimed |
| WO-1998043971-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-08 | — | — | WO | claimed |
| WO-1998042669-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-01 | — | — | WO | claimed |
| EP-1074544-B1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6388086-B1 | REACTING W 3-METHYLPYRIDINE WITH BASE; THEN EPOXY COMPOUND | KANEKA CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| US-6265409-B1 | ANTIINFLAMMATORY AGENTS | ASTRAZENECA AB (SE) | 2001-07-24 | — | — | US | disclosed |
| EP-1115705-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-07-18 | — | — | EP | disclosed |
| EP-1114029-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| EP-0984961-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-03-15 | — | — | EP | disclosed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| WO-1998043971-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-08 | — | — | WO | disclosed |
| WO-1998042669-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-01 | — | — | WO | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |