Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432185 | 0.87 | ELANE (0.38) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL9690431 | 0.87 | ELANE (0.38) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL23258853 | 0.86 | ELANE (0.37) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL25601214 | 0.86 | ELANE (0.37) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL9431775 | 0.86 | ELANE (0.37) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL9431957 | 0.81 | ELANE (0.37) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL9690416 | 0.80 | PKM (0.34) | ELANEKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL9690422 | 0.79 | ELANE (0.39) | ELANEKMT2ACASP3SENP8SENP7 | |
| SCHEMBL9432123 | 0.76 | ELANE (0.35) | ELANEKMT2AMEN1 | |
| SCHEMBL9432683 | 0.76 | ELANE (0.35) | ELANEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338733-A | Bactericides | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0564270-A1 | An isoxazolidinyl carbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |