Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PEPD | P12955 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118854 | 0.85 | TBXA2R (0.43) | KCNQ3KCNQ2SLC6A2SLC6A4TBXA2R | |
| SCHEMBL6732197 | 0.82 | SLC6A2 (0.43) | KCNQ3KCNQ2SLC6A2SLC6A4TBXA2R | |
| SCHEMBL6737612 | 0.82 | SLC6A2 (0.43) | KCNQ3KCNQ2SLC6A2SLC6A4TBXA2R | |
| SCHEMBL5839335 | 0.82 | SLC6A2 (0.43) | KCNQ3KCNQ2SLC6A2SLC6A4TBXA2R | |
| SCHEMBL8577151 | 0.82 | SLC6A2 (0.43) | KCNQ3KCNQ2SLC6A2SLC6A4TBXA2R | |
| SCHEMBL15096176 | 0.81 | FFAR1 (0.56) | FFAR1ALDH1A1 | |
| SCHEMBL7352063 | 0.80 | KCNQ3 (0.53) | KCNQ3KCNQ2SLC6A2SLC6A4FFAR1 | |
| SCHEMBL7352068 | 0.80 | KCNQ3 (0.53) | KCNQ3KCNQ2SLC6A2SLC6A4FFAR1 | |
| SCHEMBL4522521 | 0.80 | KCNQ3 (0.53) | KCNQ3KCNQ2SLC6A2SLC6A4FFAR1 | |
| SCHEMBL12592455 | 0.80 | KCNQ3 (0.53) | KCNQ3KCNQ2SLC6A2SLC6A4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011365-A1 | SUBSTITUTED BENZIMIDAZOLES AND QUINAZOLINES AS ANTIHYPERTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-05-26 | — | — | WO | disclosed |
| US-5283242-A | Hypotensive agents, cardiotonic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |