Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5839335 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL6732197 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL6737612 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL9432189 | 0.82 | KCNQ3 (0.42) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL6737892 | 0.82 | TAAR1 (0.42) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL6737896 | 0.82 | TAAR1 (0.42) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL9118854 | 0.81 | TBXA2R (0.43) | SLC6A2SLC6A4SMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL901089 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4KCNQ3KCNQ2HSD17B10 | |
| SCHEMBL838634 | 0.79 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2TAAR1 | |
| SCHEMBL22492058 | 0.79 | KCNQ3 (0.56) | SLC6A2SLC6A4KCNQ3KCNQ2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834481-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-10 | — | — | US | disclosed |
| US-5708003-A | TREATING ARTERIAL HYPERTENSION AND ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5478836-A | Treaing hypertension, atheroschlerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5395840-A | Hypotensive agents; atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |