Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20121987 | 0.86 | CASP2 (0.59) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL20121986 | 0.84 | CASP2 (0.62) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL20417361 | 0.84 | CASP2 (0.62) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL9433171 | 0.84 | CASP2 (0.57) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL20134457 | 0.84 | CASP2 (0.62) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL23567476 | 0.84 | CASP2 (0.62) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL20417364 | 0.81 | CASP2 (0.58) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL20417363 | 0.79 | CASP2 (0.56) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL4308618 | 0.79 | CASP2 (0.50) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL28527841 | 0.78 | EPHX1 (0.61) | CASP2NAAAEPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |